Changzheng Chen Selected Research

Levomilnacipran

1/2019	Relapse prevention with levomilnacipran ER in adults with major depressive disorder: A multicenter, randomized, double-blind, placebo-controlled study.
12/2017	Measures of suicidality in phase 3 clinical trials of levomilnacipran ER in adults with major depressive disorder.
3/2017	Effects of levomilnacipran ER on noradrenergic symptoms, anxiety symptoms, and functional impairment in adults with major depressive disorder: Post hoc analysis of 5 clinical trials.
1/2017	Effects of levomilnacipran extended-release on major depressive disorder patients with cognitive impairments: post-hoc analysis of a phase III study.
11/2016	Effects of levomilnacipran extended-release on motivation/energy and functioning in adults with major depressive disorder.
10/2016	The efficacy of levomilnacipran ER across symptoms of major depressive disorder: a post hoc analysis of 5 randomized, double-blind, placebo-controlled trials.
3/2016	Effects of levomilnacipran ER on fatigue symptoms associated with major depressive disorder.
4/2015	Efficacy of levomilnacipran extended-release in major depressive disorder: pooled analysis of 5 double-blind, placebo-controlled trials.
1/2015	Levomilnacipran Extended-Release Treatment in Patients With Major Depressive Disorder: Improvements in Functional Impairment Categories.
7/2014	Efficacy of levomilnacipran extended-release in improving functional impairment associated with major depressive disorder: pooled analyses of five double-blind, placebo-controlled trials.

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Changzheng Chen Research Topics

Disease

21	Major Depressive Disorder (Major Depressive Disorders) 01/2019 - 03/2013
4	COVID-19 07/2021 - 01/2020
4	Macular Degeneration (Age-Related Maculopathy) 06/2021 - 07/2004
4	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2021 - 09/2006
4	Nausea 11/2018 - 01/2014
3	Central Serous Chorioretinopathy 11/2020 - 01/2017
2	Edema (Dropsy) 11/2021 - 01/2020
2	Choroidal Neovascularization 11/2021 - 01/2015
2	Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy) 11/2021 - 01/2020
2	Retinoblastoma (Glioblastoma, Retinal) 01/2021 - 11/2020
2	Macular Edema 01/2020 - 09/2006
2	Headache (Headaches) 11/2018 - 01/2014
2	Anxiety Disorders (Anxiety Disorder) 01/2017 - 01/2016
2	Erectile Dysfunction 01/2016 - 01/2014
2	Hyperhidrosis 02/2014 - 01/2014
2	Dizziness (Lightheadedness) 02/2014 - 01/2014
2	Constipation 02/2014 - 01/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2021
1	Cataract (Cataracts) 01/2021
1	Coinfection 01/2021
1	Retinal Neovascularization 01/2021
1	Glaucoma 01/2021
1	Inflammation (Inflammations) 01/2021
1	Hypertensive Retinopathy 01/2021
1	Pathologic Neovascularization 01/2021
1	Ischemia 10/2020
1	Hemorrhage 04/2020
1	Ganglion Cysts (Ganglion) 01/2020
1	Acute-Phase Reaction 01/2020
1	Optic Nerve Diseases (Optic Neuropathy) 01/2019
1	Nasopharyngitis 11/2018
1	Diarrhea 11/2018
1	Cognitive Dysfunction 01/2017
1	Fatigue 03/2016
1	Medically Unexplained Symptoms 03/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2016
1	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2016
1	Diabetes Mellitus 01/2016
1	Ejaculatory Dysfunction 01/2016
1	Vomiting 02/2014
1	Tachycardia (Tachyarrhythmias) 02/2014
1	Sleep Initiation and Maintenance Disorders (Insomnia) 02/2014
1	Hypertension (High Blood Pressure) 02/2014
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2006
1	Epiretinal Membrane (Epiretinal Membranes) 09/2006
1	Proliferative Vitreoretinopathy 09/2006
1	Retinal Vein Occlusion 09/2006
1	Retinal Perforations 09/2006
1	Melanoma (Melanoma, Malignant) 03/2006
1	Neovascular Glaucoma 09/2005

Drug/Important Bio-Agent (IBA)

16	LevomilnacipranIBA 01/2019 - 03/2013
5	Fluorescein (Funduscein)FDA LinkGeneric 01/2021 - 09/2004
5	Retinaldehyde (Retinal)IBA 01/2021 - 01/2016
5	Vilazodone HydrochlorideIBA 11/2018 - 01/2016
4	Serotonin (5 Hydroxytryptamine)IBA 01/2019 - 10/2013
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2019 - 10/2013
3	Indocyanine Green (Cardio-Green)FDA LinkGeneric 12/2006 - 09/2004
2	Immunoglobulin M (IgM)IBA 07/2021 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 06/2021 - 11/2020
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 10/2020 - 01/2017
2	Ranibizumab (Lucentis)FDA Link 01/2016 - 01/2015
1	VincamineIBA 11/2021
1	Hormones (Hormone)IBA 11/2021
1	pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acidIBA 11/2021
1	Immunoglobulin G (IgG)IBA 07/2021
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021
1	C-Reactive ProteinIBA 01/2021
1	Insulin Receptor Substrate ProteinsIBA 01/2021
1	Circular RNAIBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	human MIRN92 microRNAIBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Silicone OilsIBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	AntigensIBA 01/2021
1	Therapeutic UsesIBA 10/2020
1	RNA (Ribonucleic Acid)IBA 08/2020
1	yttrium-aluminum-garnetIBA 04/2020
1	NeodymiumIBA 04/2020
1	rho-Associated KinasesIBA 01/2020
1	Y 27632IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	Neuroprotective AgentsIBA 01/2020
1	cariprazineIBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2017
1	Advanced Glycation End ProductsIBA 01/2016
1	Fas Ligand Protein (Fas Ligand)IBA 01/2016
1	advanced glycation end products-bovine serum albuminIBA 01/2016
1	Fibrinogen (Factor I)FDA Link 01/2015
1	Serotonin and Noradrenaline Reuptake InhibitorsIBA 01/2014
1	SuspensionsIBA 09/2006

Therapy/Procedure

3	Photochemotherapy (Photodynamic Therapy) 11/2020 - 01/2017
3	Intravitreal Injections 01/2020 - 09/2006
3	Secondary Prevention 01/2019 - 01/2014
2	Therapeutics 11/2021 - 01/2019
2	Vitrectomy 01/2021 - 09/2006
1	Nutrition Therapy (Medical Nutrition Therapy) 11/2021
1	Solid-State Lasers 04/2020
1	Lasers (Laser) 01/2020